Cephalopod eye evolution was modulated by the acquisition of Pax-6 splicing variants
نویسندگان
چکیده
منابع مشابه
Cephalopod eye evolution was modulated by the acquisition of Pax-6 splicing variants
Previous studies have reported that the developmental processes of vertebrate eyes are controlled by four Pax-6 splicing variants, each modulating different downstream genes, whereas those of insect eyes are controlled by duplicated Pax-6 genes. Cephalopods belong to the Protostomes but possess a camera-type eye similar to those in vertebrates. We examined Pax-6 variations in the squid and foun...
متن کاملIdentification of novel Pax-6 splicing variants in squids and its relevance to camera eye development of the cephalopods
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15 صفحه اولThe role of Pax-6 in eye and nasal development.
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Pax-6 is a member of the Pax gene class and encodes a protein containing a paired domain and a homeodomain. The molecular characterization of Pax-6 genes from species of different animal phyla and the analysis of Pax-6 function in the developing eyes and central nervous system of vertebrates, Drosophila melanogaster, and Caenorhabditis elegans suggest that Pax-6 homologues share conserved funct...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2014
ISSN: 2045-2322
DOI: 10.1038/srep04256